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Cryo-EM structure of SMG1–SMG8–SMG9 complex
Nonsense-mediated mRNA decay (NMD) targets premature stop codon (PTC)-containing mRNAs for rapid degradation, and is essential for mammalian embryonic development, brain development and modulation of the stress response. The key event in NMD is the SMG1-mediated phosphorylation of an RNA helicase UP...
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| Publicado no: | Cell Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6951342/ https://ncbi.nlm.nih.gov/pubmed/31729466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0255-3 |
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