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Structure of a SMG8–SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins

Nonsense-mediated mRNA decay (NMD) is a eukaryotic mRNA degradation pathway involved in surveillance and post-transcriptional regulation, and executed by the concerted action of several trans-acting factors. The SMG1 kinase is an essential NMD factor in metazoans and is associated with two recently...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Li, Liang, Lingaraju, Mahesh, Basquin, Claire, Basquin, Jérome, Conti, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473137/
https://ncbi.nlm.nih.gov/pubmed/28389433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.061200.117
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