Llwytho...

Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5–SMG7 and SMG6

Nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance pathway that recognizes mRNAs with premature stop codons and targets them for rapid degradation. Evidence from previous studies has converged on UPF1 as the central NMD factor. In human cells, the SMG1 kinase phosphorylates UPF1 at the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chakrabarti, Sutapa, Bonneau, Fabien, Schüssler, Steffen, Eppinger, Elfriede, Conti, Elena
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132714/
https://ncbi.nlm.nih.gov/pubmed/25013172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku578
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