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Cryo-EM structure of SMG1–SMG8–SMG9 complex

Nonsense-mediated mRNA decay (NMD) targets premature stop codon (PTC)-containing mRNAs for rapid degradation, and is essential for mammalian embryonic development, brain development and modulation of the stress response. The key event in NMD is the SMG1-mediated phosphorylation of an RNA helicase UP...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Res
Päätekijät: Zhu, Li, Li, Liang, Qi, Yilun, Yu, Zishuo, Xu, Yanhui
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951342/
https://ncbi.nlm.nih.gov/pubmed/31729466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0255-3
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