Cryo-EM structure of human mTOR complex 2

Mechanistic target of rapamycin (mTOR) complex 2 (mTORC2) plays an essential role in regulating cell proliferation through phosphorylating AGC protein kinase family members, including AKT, PKC and SGK1. The functional core complex consists of mTOR, mLST8, and two mTORC2-specific components, Rictor a...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Chen, Xizi, Liu, Mengjie, Tian, Yuan, Li, Jiabei, Qi, Yilun, Zhao, Dan, Wu, Zihan, Huang, Min, Wong, Catherine C. L., Wang, Hong-Wei, Wang, Jiawei, Yang, Huirong, Xu, Yanhui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951902/
https://ncbi.nlm.nih.gov/pubmed/29567957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0029-3
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