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Cryo-EM structure of human mTOR complex 2
Mechanistic target of rapamycin (mTOR) complex 2 (mTORC2) plays an essential role in regulating cell proliferation through phosphorylating AGC protein kinase family members, including AKT, PKC and SGK1. The functional core complex consists of mTOR, mLST8, and two mTORC2-specific components, Rictor a...
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| Publicado en: | Cell Res |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5951902/ https://ncbi.nlm.nih.gov/pubmed/29567957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0029-3 |
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