Cryo-EM structure of human ATR-ATRIP complex

ATR (ataxia telangiectasia-mutated and Rad3-related) protein kinase and ATRIP (ATR-interacting protein) form a complex and play a critical role in response to replication stress and DNA damage. Here, we determined the cryo-electron microscopy (EM) structure of the human ATR-ATRIP complex at 4.7 Å re...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Rao, Qinhui, Liu, Mengjie, Tian, Yuan, Wu, Zihan, Hao, Yuhan, Song, Lei, Qin, Zhaoyu, Ding, Chen, Wang, Hong-Wei, Wang, Jiawei, Xu, Yanhui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799817/
https://ncbi.nlm.nih.gov/pubmed/29271416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.158
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