Sci-Hi-C: a single-cell Hi-C method for mapping 3D genome organization in large number of single cells

The highly dynamic nature of chromosome conformation and three-dimensional (3D) genome organization leads to cell-to-cell variability in chromatin interactions within a cell population, even if the cells of the population appear to be functionally homogeneous. Hence, although Hi-C is a powerful tool...

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Vydáno v:Methods
Hlavní autoři: Ramani, Vijay, Deng, Xinxian, Qiu, Ruolan, Lee, Choli, Disteche, Christine M, Noble, William S, Shendure, Jay, Duan, Zhijun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949367/
https://ncbi.nlm.nih.gov/pubmed/31536770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2019.09.012
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