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Using DNase Hi-C techniques to map global and local three-dimensional genome architecture at high resolution
The folding and three-dimensional (3D) organization of chromatin in the nucleus critically impacts genome function. The past decade has witnessed rapid advances in genomic tools for delineating 3D genome architecture. Among them, chromosome conformation capture (3C)-based methods such as Hi-C are th...
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| Опубликовано в: : | Methods |
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| Главные авторы: | , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5993575/ https://ncbi.nlm.nih.gov/pubmed/29382556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.01.014 |
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