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Sci-Hi-C: a single-cell Hi-C method for mapping 3D genome organization in large number of single cells
The highly dynamic nature of chromosome conformation and three-dimensional (3D) genome organization leads to cell-to-cell variability in chromatin interactions within a cell population, even if the cells of the population appear to be functionally homogeneous. Hence, although Hi-C is a powerful tool...
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| Publié dans: | Methods |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6949367/ https://ncbi.nlm.nih.gov/pubmed/31536770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2019.09.012 |
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