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Mapping three-dimensional genome architecture through in situ DNase Hi-C
With the advent of massively parallel sequencing, considerable work has gone into adapting chromosome conformation capture (3C) techniques to study chromosomal architecture at genome-scale. We recently demonstrated that the inactive murine X chromosome adopts a bipartite structure using a novel 3C p...
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| Publié dans: | Nat Protoc |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5547819/ https://ncbi.nlm.nih.gov/pubmed/27685100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.126 |
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