Mapping three-dimensional genome architecture through in situ DNase Hi-C

With the advent of massively parallel sequencing, considerable work has gone into adapting chromosome conformation capture (3C) techniques to study chromosomal architecture at genome-scale. We recently demonstrated that the inactive murine X chromosome adopts a bipartite structure using a novel 3C p...

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Udgivet i:Nat Protoc
Main Authors: Ramani, Vijay, Cusanovich, Darren A, Hause, Ronald J, Ma, Wenxiu, Qiu, Ruolan, Deng, Xinxian, Blau, C. Anthony, Disteche, Christine M., Noble, William S, Shendure, Jay, Duan, Zhijun
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547819/
https://ncbi.nlm.nih.gov/pubmed/27685100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.126
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