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ALT control, delete: FANCM as an anti-cancer target in Alternative Lengthening of Telomeres
Break-induced replication is a specific type of DNA repair that has a co-opted role in telomere extension by telomerase-negative cancer cells. This Alternative Lengthening of Telomeres (or ‘ALT’) is required for viability in approximately 10% of all carcinomas, but up to 50% of the soft-tissue deriv...
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| Publicado en: | Nucleus |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6949022/ https://ncbi.nlm.nih.gov/pubmed/31663812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2019.1685246 |
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