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The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype

Telomeres are responsible for protecting chromosome ends in order to prevent the loss of coding DNA. Their maintenance is required for achieving immortality by neoplastic cells and can occur by upregulation of the telomerase enzyme or through a homologous recombination-associated process, the altern...

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Bibliografische gegevens
Gepubliceerd in:Genes (Basel)
Hoofdauteurs: Amorim, João P., Santos, Gustavo, Vinagre, João, Soares, Paula
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042396/
https://ncbi.nlm.nih.gov/pubmed/27657132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes7090066
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