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The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype

Telomeres are responsible for protecting chromosome ends in order to prevent the loss of coding DNA. Their maintenance is required for achieving immortality by neoplastic cells and can occur by upregulation of the telomerase enzyme or through a homologous recombination-associated process, the altern...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Amorim, João P., Santos, Gustavo, Vinagre, João, Soares, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042396/
https://ncbi.nlm.nih.gov/pubmed/27657132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes7090066
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