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The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype
Telomeres are responsible for protecting chromosome ends in order to prevent the loss of coding DNA. Their maintenance is required for achieving immortality by neoplastic cells and can occur by upregulation of the telomerase enzyme or through a homologous recombination-associated process, the altern...
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| Veröffentlicht in: | Genes (Basel) |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5042396/ https://ncbi.nlm.nih.gov/pubmed/27657132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes7090066 |
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