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The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype

Telomeres are responsible for protecting chromosome ends in order to prevent the loss of coding DNA. Their maintenance is required for achieving immortality by neoplastic cells and can occur by upregulation of the telomerase enzyme or through a homologous recombination-associated process, the altern...

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Bibliografske podrobnosti
izdano v:Genes (Basel)
Main Authors: Amorim, João P., Santos, Gustavo, Vinagre, João, Soares, Paula
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042396/
https://ncbi.nlm.nih.gov/pubmed/27657132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes7090066
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