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Alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas

Sarcoma is a rare and heterogeneous type of cancer with an early mean onset age and a poor prognosis. However, its genetic basis remains unclear. A series of recent genomic studies in sarcomas have identified the occurrence of mutations in the α-thalassemia/mental retardation syndrome X-linked (ATRX...

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Ren, Xiaolei, Tu, Chao, Tang, Zhenchu, Ma, Ruofei, Li, Zhihong
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920373/
https://ncbi.nlm.nih.gov/pubmed/29725455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8318
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