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Alternative Lengthening of Telomeres (ALT) in Tumors and Pluripotent Stem Cells

A telomere consists of repeated DNA sequences (TTAGGG)n as part of a nucleoprotein structure at the end of the linear chromosome, and their progressive shortening induces DNA damage response (DDR) that triggers cellular senescence. The telomere can be maintained by telomerase activity (TA) in the ma...

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Bibliografische gegevens
Gepubliceerd in:Genes (Basel)
Hoofdauteurs: Zhao, Shuang, Wang, Feng, Liu, Lin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947546/
https://ncbi.nlm.nih.gov/pubmed/31835618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10121030
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