Single-molecule analysis of subtelomeres and telomeres in Alternative Lengthening of Telomeres (ALT) cells

BACKGROUND: Telomeric DNA is typically comprised of G-rich tandem repeat motifs and maintained by telomerase (Greider CW, Blackburn EH; Cell 51:887–898; 1987). In eukaryotes lacking telomerase, a variety of DNA repair and DNA recombination based pathways for telomere maintenance have evolved in orga...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Genomics
Egile Nagusiak: Abid, Heba Z., McCaffrey, Jennifer, Raseley, Kaitlin, Young, Eleanor, Lassahn, Katy, Varapula, Dharma, Riethman, Harold, Xiao, Ming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364475/
https://ncbi.nlm.nih.gov/pubmed/32669102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-06901-7
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