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The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)
The collapse of stalled replication forks is a major driver of genomic instability. Several committed mechanisms exist to resolve replication stress. These pathways are particularly pertinent at telomeres. Cancer cells that use Alternative Lengthening of Telomeres (ALT) display heightened levels of...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6538672/ https://ncbi.nlm.nih.gov/pubmed/31138797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10180-6 |
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