Alternative lengthening of telomeres: remodeling the telomere architecture
To escape from the normal limits on proliferative potential, cancer cells must employ a means to counteract the gradual telomere attrition that accompanies semi-conservative DNA replication. While the majority of human cancers do this by up-regulating telomerase enzyme activity, most of the remainde...
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Formato: | Artigo |
Idioma: | Inglês |
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Frontiers Media S.A.
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3576624/ https://ncbi.nlm.nih.gov/pubmed/23429284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00027 |
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