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FANCM, BRCA1, and BLM cooperatively resolve the replication stress at the ALT telomeres

In the mammalian genome, certain genomic loci/regions pose greater challenges to the DNA replication machinery (i.e., the replisome) than others. Such known genomic loci/regions include centromeres, common fragile sites, subtelomeres, and telomeres. However, the detailed mechanism of how mammalian c...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pan, Xiaolei, Drosopoulos, William C., Sethi, Louisa, Madireddy, Advaitha, Schildkraut, Carl L., Zhang, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530707/
https://ncbi.nlm.nih.gov/pubmed/28673972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708065114
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