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BLM helicase facilitates telomere replication during leading strand synthesis of telomeres
Based on its in vitro unwinding activity on G-quadruplex (G4) DNA, the Bloom syndrome–associated helicase BLM is proposed to participate in telomere replication by aiding fork progression through G-rich telomeric DNA. Single molecule analysis of replicated DNA (SMARD) was used to determine the contr...
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| 發表在: | J Cell Biol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4508891/ https://ncbi.nlm.nih.gov/pubmed/26195664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201410061 |
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