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Human telomeres replicate using chromosome-specific, rather than universal, replication programs
Telomeric and adjacent subtelomeric heterochromatin pose significant challenges to the DNA replication machinery. Little is known about how replication progresses through these regions in human cells. Using single molecule analysis of replicated DNA (SMARD), we delineate the replication programs—i.e...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328383/ https://ncbi.nlm.nih.gov/pubmed/22508510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112083 |
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