Human telomeres replicate using chromosome-specific, rather than universal, replication programs

Telomeric and adjacent subtelomeric heterochromatin pose significant challenges to the DNA replication machinery. Little is known about how replication progresses through these regions in human cells. Using single molecule analysis of replicated DNA (SMARD), we delineate the replication programs—i.e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Drosopoulos, William C., Kosiyatrakul, Settapong T., Yan, Zi, Calderano, Simone G., Schildkraut, Carl L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2012
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328383/
https://ncbi.nlm.nih.gov/pubmed/22508510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112083
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