Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells

Fifteen percent of tumors utilize recombination-based alternative lengthening of telomeres (ALT) to maintain telomeres. The mechanisms underlying ALT are unclear but involve several proteins involved in homologous recombination including the BLM helicase, mutated in Bloom's syndrome, and the BR...

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Autori principali: Acharya, Samir, Kaul, Zeenia, Gocha, April Sandy, Martinez, Alaina R., Harris, Julia, Parvin, Jeffrey D., Groden, Joanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118958/
https://ncbi.nlm.nih.gov/pubmed/25084169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103819
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