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Differential requirements for DNA repair proteins in immortalized cell lines using alternative lengthening of telomere mechanisms
Cancer cells require telomere maintenance to enable uncontrolled growth. Most often telomerase is activated, although a subset of human cancers are telomerase-negative and depend on recombination-based mechanisms known as ALT (Alternative Lengthening of Telomeres). ALT depends on proteins that are e...
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| Publicado no: | Genes Chromosomes Cancer |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7170175/ https://ncbi.nlm.nih.gov/pubmed/28398700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22465 |
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