Topoisomerase IIIα is required for normal proliferation and telomere stability in alternative lengthening of telomeres

Topoisomerase (Topo) IIIα associates with BLM helicase, which is proposed to be important in the alternative lengthening of telomeres (ALT) pathway that allows telomere recombination in the absence of telomerase. Here, we show that human Topo IIIα colocalizes with telomeric proteins at ALT-associate...

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Autori principali: Temime-Smaali, Nassima, Guittat, Lionel, Wenner, Thomas, Bayart, Emilie, Douarre, Céline, Gomez, Dennis, Giraud-Panis, Marie-Josèphe, Londono-Vallejo, Arturo, Gilson, Eric, Amor-Guéret, Mounira, Riou, Jean-François
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396391/
https://ncbi.nlm.nih.gov/pubmed/18418389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.74
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