Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatin

Proper telomeric chromatin configuration is thought to be essential for telomere homeostasis and stability. Previous studies in mouse suggested that loss of heterochromatin marks at telomeres might favor onset of Alternative Lengthening of Telomeres (ALT) pathway, by promoting homologous recombinati...

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Detalhes bibliográficos
Main Authors: Episkopou, Harikleia, Draskovic, Irena, Van Beneden, Amandine, Tilman, Gaëlle, Mattiussi, Marina, Gobin, Matthieu, Arnoult, Nausica, Londoño-Vallejo, Arturo, Decottignies, Anabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985679/
https://ncbi.nlm.nih.gov/pubmed/24500201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku114
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