Genetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma Cells

Mutations in ATRX (alpha thalassemia/mental retardation syndrome X-linked), a chromatin-remodeling protein, are associated with the telomerase-independent ALT (alternative lengthening of telomeres) pathway of telomere maintenance in several types of cancer, including human gliomas. In telomerase-pos...

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Publicado en:Mol Cell Biol
Autores principales: Eid, Rita, Demattei, Marie-Véronique, Episkopou, Harikleia, Augé-Gouillou, Corinne, Decottignies, Anabelle, Grandin, Nathalie, Charbonneau, Michel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508314/
https://ncbi.nlm.nih.gov/pubmed/26055325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01317-14
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