Nuclear respiratory factor 1 and endurance exercise promote human telomere transcription

DNA breaks activate the DNA damage response and, if left unrepaired, trigger cellular senescence. Telomeres are specialized nucleoprotein structures that protect chromosome ends from persistent DNA damage response activation. Whether protection can be enhanced to counteract the age-dependent decline...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Diman, Aurélie, Boros, Joanna, Poulain, Florian, Rodriguez, Julie, Purnelle, Marin, Episkopou, Harikleia, Bertrand, Luc, Francaux, Marc, Deldicque, Louise, Decottignies, Anabelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087959/
https://ncbi.nlm.nih.gov/pubmed/27819056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600031
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