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Nuclear respiratory factor 1 and endurance exercise promote human telomere transcription
DNA breaks activate the DNA damage response and, if left unrepaired, trigger cellular senescence. Telomeres are specialized nucleoprotein structures that protect chromosome ends from persistent DNA damage response activation. Whether protection can be enhanced to counteract the age-dependent decline...
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| Veröffentlicht in: | Sci Adv |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Association for the Advancement of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087959/ https://ncbi.nlm.nih.gov/pubmed/27819056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600031 |
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