Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatin

Proper telomeric chromatin configuration is thought to be essential for telomere homeostasis and stability. Previous studies in mouse suggested that loss of heterochromatin marks at telomeres might favor onset of Alternative Lengthening of Telomeres (ALT) pathway, by promoting homologous recombinati...

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Bibliografische gegevens
Hoofdauteurs: Episkopou, Harikleia, Draskovic, Irena, Van Beneden, Amandine, Tilman, Gaëlle, Mattiussi, Marina, Gobin, Matthieu, Arnoult, Nausica, Londoño-Vallejo, Arturo, Decottignies, Anabelle
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
Onderwerpen:
Gene Regulation, Chromatin and Epigenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985679/
https://ncbi.nlm.nih.gov/pubmed/24500201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku114
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