Cancer-linked satellite 2 DNA hypomethylation does not regulate Sat2 non-coding RNA expression and is initiated by heat shock pathway activation

Epigenetic dysfunctions, including DNA methylation alterations, play major roles in cancer initiation and progression. Although it is well established that gene promoter demethylation activates transcription, it remains unclear whether hypomethylation of repetitive heterochromatin similarly affects...

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Главные авторы: Tilman, Gaëlle, Arnoult, Nausica, Lenglez, Sandrine, Van Beneden, Amandine, Loriot, Axelle, De Smet, Charles, Decottignies, Anabelle
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2012
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427286/
https://ncbi.nlm.nih.gov/pubmed/22722874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.21107
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