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Cancer-linked satellite 2 DNA hypomethylation does not regulate Sat2 non-coding RNA expression and is initiated by heat shock pathway activation

Epigenetic dysfunctions, including DNA methylation alterations, play major roles in cancer initiation and progression. Although it is well established that gene promoter demethylation activates transcription, it remains unclear whether hypomethylation of repetitive heterochromatin similarly affects...

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Bibliografske podrobnosti
Main Authors: Tilman, Gaëlle, Arnoult, Nausica, Lenglez, Sandrine, Van Beneden, Amandine, Loriot, Axelle, De Smet, Charles, Decottignies, Anabelle
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427286/
https://ncbi.nlm.nih.gov/pubmed/22722874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.21107
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