A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors

Genome hypomethylation is a common epigenetic alteration in human tumors, where it often leads to aberrant activation of a group of germline-specific genes, commonly referred to as “cancer-germline” genes. The cellular functions and tumor promoting potential of these genes remain, however, largely u...

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Detalhes bibliográficos
Main Authors: Loriot, Axelle, Van Tongelen, Aurélie, Blanco, Jordi, Klaessens, Simon, Cannuyer, Julie, van Baren, Nicolas, Decottignies, Anabelle, De Smet, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164501/
https://ncbi.nlm.nih.gov/pubmed/25089631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.29628
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