miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2

Myelofibrosis (MF) is a myeloproliferative neoplasm characterized by cytopenia and extramedullary hematopoiesis, resulting in splenomegaly. Multiple pathological mechanisms (e.g., circulating cytokines and genetic alterations, such as JAK(V617F) mutation) have been implicated in the etiology of MF,...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Fuentes-Mattei, Enrique, Bayraktar, Recep, Manshouri, Taghi, Silva, Andreia M., Ivan, Cristina, Gulei, Diana, Fabris, Linda, Soares do Amaral, Nayra, Mur, Pilar, Perez, Cristina, Torres-Claudio, Elizabeth, Dragomir, Mihnea P., Badillo-Perez, Adriana, Knutsen, Erik, Narayanan, Pranav, Golfman, Leonard, Shimizu, Masayoshi, Zhang, Xinna, Zhao, Wanke, Ho, Wanting Tina, Estecio, Marcos Roberto, Bartholomeusz, Geoffrey, Tomuleasa, Ciprian, Berindan-Neagoe, Ioana, Zweidler-McKay, Patrick A., Estrov, Zeev, Zhao, Zhizhuang J., Verstovsek, Srdan, Calin, George A., Redis, Roxana S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030823/
https://ncbi.nlm.nih.gov/pubmed/31941838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121781
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