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A gene expression signature identifying transient DNMT1 depletion as a causal factor of cancer-germline gene activation in melanoma
BACKGROUND: Many human tumors show aberrant activation of a group of germline-specific genes, termed cancer-germline (CG) genes, several of which appear to exert oncogenic functions. Although activation of CG genes in tumors has been linked to promoter DNA demethylation, the mechanisms underlying th...
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| Publicado no: | Clin Epigenetics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4620642/ https://ncbi.nlm.nih.gov/pubmed/26504497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0147-4 |
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