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Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein Composition

Protecting telomere from the DNA damage response is essential to avoid the entry into cellular senescence and organismal aging. The progressive telomere DNA shortening in dividing somatic cells, programmed during development, leads to critically short telomeres that trigger replicative senescence an...

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Publicat a:Cells
Autors principals: Ghilain, Claire, Gilson, Eric, Giraud-Panis, Marie-Josèphe
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305809/
https://ncbi.nlm.nih.gov/pubmed/34359923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071753
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