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Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein Composition

Protecting telomere from the DNA damage response is essential to avoid the entry into cellular senescence and organismal aging. The progressive telomere DNA shortening in dividing somatic cells, programmed during development, leads to critically short telomeres that trigger replicative senescence an...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Ghilain, Claire, Gilson, Eric, Giraud-Panis, Marie-Josèphe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305809/
https://ncbi.nlm.nih.gov/pubmed/34359923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071753
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