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Blockade of glutathione metabolism in IDH1-mutated glioma
Mutations in genes encoding isocitrate dehydrogenases (IDHs) 1 and 2 are common cancer-related genetic abnormalities. Malignancies with mutated IDHs exhibit similar pathogenesis, metabolic pattern, and resistance signature. However, an effective therapy against IDH1-mutated solid tumor remains unava...
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| Gepubliceerd in: | Mol Cancer Ther |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6946871/ https://ncbi.nlm.nih.gov/pubmed/31548295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0103 |
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