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DDRE-08. NRF2/GLUTATHIONE METABOLISM AS A NOVEL THERAPEUTIC TARGET FOR IDH1-MUTATED GLIOMA

BACKGROUND: IDH1-mutated glioma is a recently defined disease entity with distinctive patterns of tumor cell biology, metabolism, and resistance to therapy. Although IDH1 mutations are highly prevalent in patients with WHO II/III glioma, curative molecular targeting approaches remain unavailable for...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Liu, Yang, Yu, Di, Celiku, Orieta, Li, Aiguo, Larion, Mioara, Yang, Chunzhang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992271/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.030
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