DDRE-20. TARGETING SPHINGOLIPID PATHWAY REVEALS VULNERABILITY IN IDH1(MUT) GLIOMA

BACKGROUND: While central carbon metabolism has been studied extensively in cancer, lipidomic research is sparse. Sphingolipids participate in cellular functions including secondary messengers, lymphocyte trafficking, inflammation, angiogenesis, migration, proliferation, necrosis and apoptosis, thus...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neurooncol Adv
Main Authors: Dowdy, Tyrone, Zhang, Lumin, Celiku, Orieta, Movva, Sriya, Ruiz-Rodado, Victor, Lita, Adrian, Larion, Mioara
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Supplement Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992217/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.042
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