DDRE-20. TARGETING SPHINGOLIPID PATHWAY REVEALS VULNERABILITY IN IDH1(MUT) GLIOMA

BACKGROUND: While central carbon metabolism has been studied extensively in cancer, lipidomic research is sparse. Sphingolipids participate in cellular functions including secondary messengers, lymphocyte trafficking, inflammation, angiogenesis, migration, proliferation, necrosis and apoptosis, thus...

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Bibliographic Details
Published in:Neurooncol Adv
Main Authors: Dowdy, Tyrone, Zhang, Lumin, Celiku, Orieta, Movva, Sriya, Ruiz-Rodado, Victor, Lita, Adrian, Larion, Mioara
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992217/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.042
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