DDRE-20. TARGETING SPHINGOLIPID PATHWAY REVEALS VULNERABILITY IN IDH1(MUT) GLIOMA

BACKGROUND: While central carbon metabolism has been studied extensively in cancer, lipidomic research is sparse. Sphingolipids participate in cellular functions including secondary messengers, lymphocyte trafficking, inflammation, angiogenesis, migration, proliferation, necrosis and apoptosis, thus...

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Publicado en:Neurooncol Adv
Autores principales: Dowdy, Tyrone, Zhang, Lumin, Celiku, Orieta, Movva, Sriya, Ruiz-Rodado, Victor, Lita, Adrian, Larion, Mioara
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
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Supplement Abstracts
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992217/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.042
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