DDRE-20. TARGETING SPHINGOLIPID PATHWAY REVEALS VULNERABILITY IN IDH1(MUT) GLIOMA

BACKGROUND: While central carbon metabolism has been studied extensively in cancer, lipidomic research is sparse. Sphingolipids participate in cellular functions including secondary messengers, lymphocyte trafficking, inflammation, angiogenesis, migration, proliferation, necrosis and apoptosis, thus...

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Foilsithe in:Neurooncol Adv
Main Authors: Dowdy, Tyrone, Zhang, Lumin, Celiku, Orieta, Movva, Sriya, Ruiz-Rodado, Victor, Lita, Adrian, Larion, Mioara
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2021
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Supplement Abstracts
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992217/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.042
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