Načítá se...
Targeting IDH1-Mutated Malignancies with NRF2 Blockade
BACKGROUND: Neomorphic IDH1 mutations disrupt the redox balance by promoting reactive oxygen species (ROS) production. However, the mechanism by which IDH1-mutant cells maintain ROS homeostasis remains elusive. It is also not known whether reprogrammed ROS homeostasis establishes targetable vulnerab...
Uloženo v:
| Vydáno v: | J Natl Cancer Inst |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2019
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6792082/ https://ncbi.nlm.nih.gov/pubmed/30759236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djy230 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|