High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis

OBJECTIVE: We examined whether plasma β-amyloid (Aβ)42/Aβ40, as measured by a high-precision assay, accurately diagnosed brain amyloidosis using amyloid PET or CSF p-tau181/Aβ42 as reference standards. METHODS: Using an immunoprecipitation and liquid chromatography–mass spectrometry assay, we measur...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Schindler, Suzanne E., Bollinger, James G., Ovod, Vitaliy, Mawuenyega, Kwasi G., Li, Yan, Gordon, Brian A., Holtzman, David M., Morris, John C., Benzinger, Tammie L.S., Xiong, Chengjie, Fagan, Anne M., Bateman, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946467/
https://ncbi.nlm.nih.gov/pubmed/31371569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000008081
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