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Defective postreplication repair of UV photoproducts in melanoma: a mutator phenotype

In this issue, the Gabrielli laboratory and collaborators address the bulky CPD lesions created in DNA when UV joins two adjacent pyrimidines (thymine or cytosine), leading to skin cancers such as melanoma (Pavey S et al. (2019) Mol Oncol). Our understanding of postreplication repair mechanisms for...

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書目詳細資料
發表在:Mol Oncol
Main Authors: Brash, Douglas E., Seidman, Michael M.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944110/
https://ncbi.nlm.nih.gov/pubmed/31821728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12612
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