Multiple interaction nodes define the postreplication repair response to UV‐induced DNA damage that is defective in melanomas and correlated with UV signature mutation load

Ultraviolet radiation‐induced DNA mutations are a primary environmental driver of melanoma. The reason for this very high level of unrepaired DNA lesions leading to these mutations is still poorly understood. The primary DNA repair mechanism for UV‐induced lesions, that is, the nucleotide excision r...

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Vydáno v:Mol Oncol
Hlavní autoři: Pavey, Sandra, Pinder, Alex, Fernando, Winnie, D’Arcy, Nicholas, Matigian, Nicholas, Skalamera, Dubravka, Lê Cao, Kim‐Anh, Loo‐Oey, Dorothy, Hill, Michelle M., Stark, Mitchell, Kimlin, Michael, Burgess, Andrew, Cloonan, Nicole, Sturm, Richard A., Gabrielli, Brian
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944116/
https://ncbi.nlm.nih.gov/pubmed/31733171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12601
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