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Postreplication gaps at UV lesions are signals for checkpoint activation

Exposure of eukaryotic cells to UV light induces a checkpoint response that delays cell-cycle progression after cells enter S phase. It has been hypothesized that this checkpoint response provides time for repair by signaling the presence of structures generated when the replication fork encounters...

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Autors principals: Callegari, A. John, Clark, Emily, Pneuman, Amanda, Kelly, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889594/
https://ncbi.nlm.nih.gov/pubmed/20404181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003449107
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