Multiple interaction nodes define the postreplication repair response to UV‐induced DNA damage that is defective in melanomas and correlated with UV signature mutation load

Ultraviolet radiation‐induced DNA mutations are a primary environmental driver of melanoma. The reason for this very high level of unrepaired DNA lesions leading to these mutations is still poorly understood. The primary DNA repair mechanism for UV‐induced lesions, that is, the nucleotide excision r...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Pavey, Sandra, Pinder, Alex, Fernando, Winnie, D’Arcy, Nicholas, Matigian, Nicholas, Skalamera, Dubravka, Lê Cao, Kim‐Anh, Loo‐Oey, Dorothy, Hill, Michelle M., Stark, Mitchell, Kimlin, Michael, Burgess, Andrew, Cloonan, Nicole, Sturm, Richard A., Gabrielli, Brian
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944116/
https://ncbi.nlm.nih.gov/pubmed/31733171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12601
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