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Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells.
The role of UV radiation-induced photoproducts in initiating base substitution mutations in human cells was examined by measuring photoproduct frequency distributions and mutations in a supF tRNA gene on a shuttle vector plasmid transfected into DNA repair-deficient cells (xeroderma pigmentosum, com...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1987
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3473483/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.11.3782 |
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