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Binding of transcription factors creates hot spots for UV photoproducts in vivo.

Cyclobutane dipyrimidines and less than mean value of 6-4 dipyrimidines are the two major classes of mutagenic DNA photoproducts produced by UV irradiation of cells. We developed a method to map cyclobutane dipyrimidines at the DNA sequence level in mammalian cells. The frequency of this class of ph...

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Detalhes bibliográficos
Main Authors: Pfeifer, G P, Drouin, R, Riggs, A D, Holmquist, G P
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369623/
https://ncbi.nlm.nih.gov/pubmed/1549126
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