Wird geladen...
Relationship between Hot Spot Residues and Ligand Binding Hot Spots in Protein-Protein Interfaces
In the context of protein-protein interactions, the term “hot spot” refers to a residue or cluster of residues that makes a major contribution to the binding free energy, as determined by alanine scanning mutagenesis. In contrast, in pharmaceutical research a hot spot is a site on a target protein t...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623692/ https://ncbi.nlm.nih.gov/pubmed/22770357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci300175u |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|