A transcriptionally-definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to HSP90 inhibition

PURPOSE: We hypothesized that integrated analysis of cancer types from different lineages would reveal novel molecularly defined subgroups with unique therapeutic vulnerabilities. Based on the molecular similarities between subgroups of breast and ovarian cancers, we analyzed these cancers as a sing...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Clin Cancer Res
Main Authors: Shee, Kevin, Wells, Jason D., Ung, Matthew, Hampsch, Riley A., Traphagen, Nicole A., Yang, Wei, Liu, Stephanie, Zeldenrust, Megan A., Wang, Liewei, Kalari, Krishna R., Yu, Jia, Boughey, Judy C., Demidenko, Eugene, Kettenbach, Arminja N., Cheng, Chao, Goetz, Matthew P., Miller, Todd W.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2019
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942625/
https://ncbi.nlm.nih.gov/pubmed/31558472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2213
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