A transcriptionally-definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to HSP90 inhibition

PURPOSE: We hypothesized that integrated analysis of cancer types from different lineages would reveal novel molecularly defined subgroups with unique therapeutic vulnerabilities. Based on the molecular similarities between subgroups of breast and ovarian cancers, we analyzed these cancers as a sing...

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Publicado no:Clin Cancer Res
Main Authors: Shee, Kevin, Wells, Jason D., Ung, Matthew, Hampsch, Riley A., Traphagen, Nicole A., Yang, Wei, Liu, Stephanie, Zeldenrust, Megan A., Wang, Liewei, Kalari, Krishna R., Yu, Jia, Boughey, Judy C., Demidenko, Eugene, Kettenbach, Arminja N., Cheng, Chao, Goetz, Matthew P., Miller, Todd W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942625/
https://ncbi.nlm.nih.gov/pubmed/31558472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2213
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