A transcriptionally-definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to HSP90 inhibition

PURPOSE: We hypothesized that integrated analysis of cancer types from different lineages would reveal novel molecularly defined subgroups with unique therapeutic vulnerabilities. Based on the molecular similarities between subgroups of breast and ovarian cancers, we analyzed these cancers as a sing...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Shee, Kevin, Wells, Jason D., Ung, Matthew, Hampsch, Riley A., Traphagen, Nicole A., Yang, Wei, Liu, Stephanie, Zeldenrust, Megan A., Wang, Liewei, Kalari, Krishna R., Yu, Jia, Boughey, Judy C., Demidenko, Eugene, Kettenbach, Arminja N., Cheng, Chao, Goetz, Matthew P., Miller, Todd W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942625/
https://ncbi.nlm.nih.gov/pubmed/31558472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2213
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